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What Is The Mechanism Of Action Of Suhagra 50 Mg?
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Sep 14, 2024
5:15 AM
 

Suhagra 50 mg is a medication used to treat erectile dysfunction (ED). Its active ingredient is Sildenafil Citrate, which is also the active component in other well-known ED treatments like Viagra.

Mechanism of Action of Suhagra 50 mg
1. Inhibition of PDE5:
Phosphodiesterase Type 5 (PDE5) Inhibition: Sildenafil Citrate works by inhibiting the enzyme PDE5. PDE5 is responsible for the breakdown of cyclic guanosine monophosphate (cGMP), a molecule that helps regulate blood flow in the penis.

2. Increased cGMP Levels:
cGMP Accumulation: By inhibiting PDE5, Suhagra 50 mg leads to increased levels of cGMP in the smooth muscle cells of the penis. cGMP is a key mediator in the process of vasodilation, which involves the relaxation of smooth muscle and widening of blood vessels.

3. Enhanced Blood Flow:
Vasodilation: The increase in cGMP levels causes the smooth muscles in the blood vessels of the penis to relax. This relaxation leads to the dilation of these blood vessels, resulting in increased blood flow to the penile tissues.

4. Erection Induction:
Improved Erection: The enhanced blood flow fills the penile tissues, leading to an erection in response to sexual stimulation. It's important to note that sexual stimulation is required for SUHAGRA 50 MG to be effective, as it does not induce an erection on its own.

5. Duration and Onset:
Onset of Action: Suhagra 50 mg typically starts to work within 30 to 60 minutes after ingestion.

Duration: The effects generally last for about 4 to 6 hours, allowing for a satisfactory window of opportunity for sexual activity.

Summary
Suhagra 50 mg functions primarily through the inhibition of the PDE5 enzyme, which leads to increased levels of cGMP. This results in the relaxation of smooth muscle and dilation of blood vessels in the penis, thereby improving blood flow and facilitating an erection in response to sexual stimulation. It does not induce an erection on its own and requires sexual arousal to be effective.


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