Bioglandin Injection, which contains Alprostadil, is used to treat erectile dysfunction (ED) and sometimes for other medical conditions. Alprostadil works by relaxing blood vessels and increasing blood flow to the penis or other areas. However, there are specific contraindications and precautions associated with its use, including:

Hypersensitivity: Individuals who are allergic to Alprostadil or any of the other components of the injection should avoid using it.

Penile Conditions: Patients with certain penile conditions, such as Peyronie's disease or severe penile curvature, should avoid Alprostadil injections due to the risk of exacerbating these conditions or causing other complications.

History of Priapism: Those with a history of priapism (prolonged and painful erections) should not use Bioglandin Injection, as it may increase the risk of this condition.

Severe Cardiovascular Conditions: Individuals with severe cardiovascular conditions or unstable angina should be cautious, as Bioglandin Injection can affect blood pressure and cardiovascular function.

Sickle Cell Anemia: Patients with sickle cell anemia or other blood disorders should avoid using Alprostadil due to the risk of complications related to blood flow and clotting.

Pregnancy and Lactation: Alprostadil is not recommended for use in pregnant women or breastfeeding mothers, as its effects on these populations have not been well-studied.

Medication Interactions: Alprostadil should be used cautiously with other medications that affect blood pressure or blood flow, including certain antihypertensives or anticoagulants.

Always consult with a healthcare provider to discuss any contraindications and to determine if Bioglandin Injection is appropriate for your specific situation. They can provide guidance based on your health status, medical history, and any potential risks associated with the medication.