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Manforce 100 Mg
Manforce 100 Mg
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Ronymeran
Guest
May 03, 2024
11:41 PM
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What Is the Mechanism of Action of Manforce 100 Mg ?
Manforce 100 mg contains sildenafil citrate as its active ingredient. Sildenafil citrate is a type of medication known as a phosphodiesterase type 5 (PDE5) inhibitor. Here's how it works:
Relaxation of Blood Vessels: When a man is sexually aroused, nitric oxide (NO) is released in the erectile tissue of the penis. Nitric oxide then activates an enzyme called guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP). cGMP is responsible for relaxing the smooth muscles and dilating the blood vessels in the penis, allowing blood to flow in and create an erection.
Inhibition of PDE5: The enzyme phosphodiesterase type 5 (PDE5) is responsible for breaking down cGMP. By inhibiting PDE5, sildenafil citrate allows cGMP levels to remain elevated for a longer duration. This prolongs the relaxation of smooth muscles and vasodilation in the penis, promoting and maintaining an erection.
In summary, the mechanism of action of Manforce 100 mg involves enhancing the effects of nitric oxide, increasing levels of cGMP, and inhibiting the enzyme PDE5, ultimately leading to improved blood flow to the penis and the ability to achieve and maintain an erection during sexual stimulation. It's important to note that sexual stimulation is still required for the medication to be effective.
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